By Marek Los, Henning Walczak

ISBN-10: 0306474417

ISBN-13: 9780306474415

ISBN-10: 1587061325

ISBN-13: 9781587061325

The amount deals perception into the foremost study subject matters that contain caspases. best specialists from quite a few parts of biology and drugs have compiled this quantity in order that either the amateur and the pro will use this because the major reference for caspases for future years. The reader will know about the position of caspases in apoptosis signaling, irritation and melanoma remedy whereas being up to date at the method used to check caspases and the efforts of pharmaceutical examine in focusing on caspases.

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Extra info for Caspases: Their Role in Cell Death and Cell Survival (Molecular Biology Intelligence Unit)

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Van de Craen M, Vandenabeele P, Declercq W et al. Characterization of seven murine caspase family members. FEBS Lett 1997; 403:61-69. 10. Cikala M, Wilm B, Hobmayer E et al. Identification of caspases and apoptosis in the simple metazoan Hydra. Curr Biol 1999; 9:959-962. 11. Miossec C, Dutilleul V, Fassy F et al. Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation. J Biol Chem 1997; 272:13459-13462. 12. Alam A, Cohen LY, Aouad S et al. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells.

J Biol Chem 1999; 274:8359-62. 36. Roy S, Bayly CI, Gareau Y et al. Maintenance of caspase-3 proenzyme dormancy by an itrinsic „safety catch“ regulatory tripeptide. Proc Natl Acad Sci USA 2001; 98:6132-7. 37. Martin SJ, Amarante-Mendes GP, Shi L et al. The cytotoxic cell protease granzyme B initiates apoptosis in a cell- free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism. EMBO J 1996; 15:2407-16. 38. Thornberry NA, Rano TA, Peterson EP et al.

Cell Mol Life Sci 2001; 58:356-370. 24. Leist M, Jaattela M. Four deaths and a funeral: From caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001; 2:589-598. 25. Babior BM, Matzner Y. The familial Mediterranean fever gene-cloned at last. N Engl J Med 1997; 337:1548-1549. 26. Gu Y, Wu J, Faucheu C et al. Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo. EMBO J 1995; 14:1923-1931. 27. Muzio M, Stockwell BR, Stennicke HR et al. An induced proximity model for caspase-8 activation.

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Caspases: Their Role in Cell Death and Cell Survival (Molecular Biology Intelligence Unit) by Marek Los, Henning Walczak


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