By Jason A. Burdick, Robert L. Mauck

ISBN-10: 3709103843

ISBN-13: 9783709103845

ISBN-10: 3709103851

ISBN-13: 9783709103852

A concise evaluate of tissue engineering applied sciences and fabrics in the direction of particular purposes, either prior and capability development parts during this exact self-discipline is equipped to the reader. the categorical zone of the biomaterial part used in the paradigm of tissue engineering is tested intimately. this can be the 1st paintings to in particular covers themes of curiosity on the subject of the biomaterial part. The publication is split into 2 sections: (i) basic fabrics know-how (e.g., fibrous tissue scaffolds) and (ii) functions within the engineering of particular tissues (e.g., fabrics for cartilage tissue engineering). each one bankruptcy covers the basics and displays not just a evaluate of the literature, but in addition addresses the way forward for the subject. The booklet is meant for an viewers of researchers in either and academia which are attracted to a concise evaluation concerning the biomaterials section of tissue engineering, a subject that's well timed and basically transforming into as a field.

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Extra resources for Biomaterials for Tissue Engineering Applications: A Review of the Past and Future Trends

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Fujiwara T, Mukose T, Yamaoka T, Yamane H, Sakurai S, Kimura Y. Novel thermo-responsive formation of a hydrogel by stereo-complexation between PLLA-PEG-PLLA and PDLAPEG-PDLA block copolymers. Macromol Biosci 2001;1:204–8. 78. Koopmans C, Ritter H. Formation of physical hydrogels via Host−guest interactions of β-cyclodextrin polymers and copolymers bearing adamantyl groups. Macromolecules 2008; 41:7418–22. 79. Ulijn RV, Smith AM. Designing peptide based nanomaterials. Chem Soc Rev 2008;37: 664–75.

Fujiwara T, Mukose T, Yamaoka T, Yamane H, Sakurai S, Kimura Y. Novel thermo-responsive formation of a hydrogel by stereo-complexation between PLLA-PEG-PLLA and PDLAPEG-PDLA block copolymers. Macromol Biosci 2001;1:204–8. 78. Koopmans C, Ritter H. Formation of physical hydrogels via Host−guest interactions of β-cyclodextrin polymers and copolymers bearing adamantyl groups. Macromolecules 2008; 41:7418–22. 79. Ulijn RV, Smith AM. Designing peptide based nanomaterials. Chem Soc Rev 2008;37: 664–75.

The ability to manipulate material properties or chemistry in real time in a spatial manner provides dynamic environments to regulate cellular functions. 3 Enzymatically Degradable Hydrogels A more biomimetic approach for hydrogel degradation relies on the enzymes secreted by the cells, including the cysteine and serine proteases and matrix metalloproteinases (MMPs), all of which target specific cleavage sites on ECM proteins and proteoglycans. MMP-cleavable peptide sequences have been identified and incorporated as crosslinking motifs in synthetic hydrogels to enable cell-mediated proteolysis.

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Biomaterials for Tissue Engineering Applications: A Review of the Past and Future Trends by Jason A. Burdick, Robert L. Mauck


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