By Luiz Junqueira, Jose Carneiro

ISBN-10: 0071440917

ISBN-13: 9780071440912

The best textual content of scientific histology and microscopic anatomy!
A Doody's middle Title
With a full-color layout and OVER six hundred photomicrographs and illustrations, this booklet is still the main authoritative histology textual content out there. Revised to mirror the most recent study within the box, this booklet emphasizes the relationships and ideas that hyperlink phone and tissue buildings with their capabilities. an advantage snapshot library CD-ROM that includes all of the pictures and illustrations from the textual content with “zoom in” and “zoom out” potential can also be incorporated.

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Nat. , 14, 767–772. A. (2010) Defining the mechanism of polymerization in the serpinopathies. Proc. Natl. Acad. Sci. , 107, 17146–17151. , and Lollar, P. (2011) Factor VIII A3 domain substitution N1922S results in hemophilia A due to domain-specific misfolding and hyposecretion of functional protein. Blood, 117 (11), 3190–3198. , and Appenzeller, C. (2000) ERGIC-53 and traffic in the secretory pathway. J. , 113 (Pt 4), 587–596. C. (2004) Finishing the euchromatic sequence of the human genome. Nature, 431, 931–945.

Their roles in basic biological process as well as in several pathologies suggest the importance of these enzymes. This dual implication of proteases in life and disease should always be taken into consideration before dealing with clinical applications, but hopefully, the increasing knowledge of these enzymes will contribute to understand their diverse functional roles in vivo and to identify new therapeutic targets. Acknowledgments Our work is supported by grants from the Ministerio de Ciencia e Innovaci´on-Spain, Fundaci´on ‘‘M.

2002) A quantitative-trait locus in the human factor XII gene influences both plasma 53. 54. 55. 56. 57. 58. 59. 60. factor XII levels and susceptibility to thrombotic disease. Am. J. Hum. , 70, 567–574. E. (2001) Increased efficiency of mRNA 3’ end formation: a new genetic mechanism contributing to hereditary thrombophilia. Nat. , 28, 389–392. L. C. (2008) Abnormalities of prothrombin: a review of the pathophysiology, diagnosis, and treatment. Haemophilia, 14, 1159–1163. , Gruppo, R. et al. (2001) Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura.

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Basic Histology. Text and Atlas by Luiz Junqueira, Jose Carneiro

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